PRKCE

Across TCGA cell cohorts, PRKCE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,845 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRKCE-associated GO terms across cancer lineages are TRAM-dependent toll-like receptor signaling pathway, TRAM-dependent toll-like receptor 4 signaling pathway, and Regulation of hippo signaling. Each is linked with PRKCE in more than 15 cancer types. Because this analysis shows association rather than direction, both PRKCE-to-partner and partner-to-PRKCE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAM-dependent toll-like receptor signaling pathway grouped by PRKCE-low versus PRKCE-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCE→partner) and Y-score (partner→PRKCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	TRAM-dependent toll-like receptor signaling pathway →	+1.115	+1.618	.003	.002	3	16
LIVER	TRAM-dependent toll-like receptor 4 signaling pathway →	+1.115	+1.618	.003	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of hippo signaling →	+0.068	+0.922	.003	.005	3	11
SOFT_TISSUE	Phosphatidylinositol biosynthetic process →	+0.046	+1.276	<.001	.004	3	11
CNS	Regulation of stress-activated protein kinase signaling cascade →	+0.097	+1.079	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.053	+0.876	<.001	.005	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,845 associations by consensus.

TRAM-dependent toll-like receptor signaling pathway by PRKCE expression — LIVER

Explore this box plot interactively →