Across TCGA pan-cancer cohorts, PRKCE-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of PRKCE-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where PRKCE-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types PRKCE-AS1 is over-expressed in tumor, although a few such as UCEC and KIRC show the opposite, repressed pattern.

UCEC, KIRC, and KICH are the cancer types where PRKCE-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PRKCE-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	III,IV	−0.361	.034	8	view →
KIRC	All	II,III,IV	−0.059	.007	4	view →
KICH	All	All	−0.112	.002	3	view →
HNSC	Male	All	+0.113	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: PRKCE-AS1 RNA expression & survival · all PRKCE-AS1 data types