PRKACG

Across TCGA patient cohorts, PRKACG RNA expression is significantly associated with the go_rna of many other GO terms, with 6,794 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRKACG-associated GO terms across cancer lineages are Protein targeting to vacuole, Positive regulation of canonical Wnt signaling pathway, and Regulation of cell projection assembly. Each is linked with PRKACG in more than 14 cancer types. Because this analysis shows association rather than direction, both PRKACG-to-partner and partner-to-PRKACG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to vacuole grouped by PRKACG-low versus PRKACG-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKACG→partner) and Y-score (partner→PRKACG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein targeting to vacuole →	+0.053	+0.102	<.001	<.001	3	15
STAD	Positive regulation of canonical Wnt signaling pathway →	+0.051	+0.093	<.001	<.001	3	14
STAD	Regulation of cell projection assembly →	+0.049	+0.100	<.001	<.001	3	14
STAD	Protein localization to vacuole →	+0.055	+0.104	<.001	<.001	3	14
STAD	Protein localization to plasma membrane →	+0.050	+0.084	<.001	<.001	3	14
STAD	Regulation of autophagosome assembly →	+0.055	+0.093	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,794 associations by consensus.

Protein targeting to vacuole by PRKACG expression — STAD

Explore this box plot interactively →