PRKACB

Across TCGA patient cohorts, PRKACB RNA expression is significantly associated with the protein abundance of many other proteins, with 17,365 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRKACB-associated proteins across cancer lineages are IMP4, RSL1D1, and SEPTIN1. Each is linked with PRKACB in more than 4 cancer types. Because this analysis shows association rather than direction, both PRKACB-to-partner and partner-to-PRKACB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKACB versus IMP4 in BRCA, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKACB→partner) and Y-score (partner→PRKACB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IMP4 →	-0.305	-1.470	.004	.001	3	5
GBM	RSL1D1 →	-0.350	-0.465	<.001	<.001	3	5
LSCC	SEPTIN1 →	+0.750	+0.663	<.001	<.001	3	5
OV	SEPTIN6 →	+0.453	+0.759	<.001	.002	3	5
HNSC	VPS13C →	+0.351	+0.558	<.001	.009	3	5
GBM	CAMK4 →	+0.540	+0.528	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,365 associations by consensus.

PRKACB vs IMP4 — BRCA

Explore this scatter interactively →