PRKAA1

Across TCGA patient cohorts, PRKAA1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,514 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRKAA1-associated genes across cancer lineages are PRKAB1, FOXM1, and CHP1. Each is linked with PRKAA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRKAA1-to-partner and partner-to-PRKAA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKAA1 versus PRKAB1 in LUAD, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAA1→partner) and Y-score (partner→PRKAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRKAB1 →	+0.552	+0.154	<.001	<.001	3	7
GBM	FOXM1 →	-1.113	-0.231	<.001	<.001	3	5
LSCC	CHP1 →	+0.418	+0.178	<.001	.001	3	5
CCRCC	TMBIM6 →	+0.475	+0.186	<.001	<.001	3	5
OV	RPL22P12 →	-2.392	-0.304	<.001	<.001	3	4
OV	G3BP1P1 →	-0.920	-0.319	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,514 associations by consensus.

PRKAA1 vs PRKAB1 — LUAD

Explore this scatter interactively →