PRKAA1

Across TCGA cell cohorts, PRKAA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,423 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRKAA1-associated GO terms across cancer lineages are Protein localization to lipid droplet, Establishment of RNA localization, and Phosphatidylinositol biosynthetic process. Each is linked with PRKAA1 in more than 18 cancer types. Because this analysis shows association rather than direction, both PRKAA1-to-partner and partner-to-PRKAA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to lipid droplet grouped by PRKAA1-low versus PRKAA1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAA1→partner) and Y-score (partner→PRKAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein localization to lipid droplet →	+0.205	+1.122	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.103	+1.575	.001	<.001	3	15
CNS	Phosphatidylinositol biosynthetic process →	+0.047	+0.676	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Nucleic acid transport →	+0.103	+1.527	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	RNA transport →	+0.103	+1.527	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	mRNA export from nucleus →	+0.116	+1.312	.004	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,423 associations by consensus.

Protein localization to lipid droplet by PRKAA1 expression — BONE

Explore this box plot interactively →