PRIM1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRIM1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,491 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRIM1-associated genes across cancer lineages are RAD51AP1, TOP2A, and FANCI. Each is linked with PRIM1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PRIM1-to-partner and partner-to-PRIM1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRIM1→partner) and Y-score (partner→PRIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRAD51AP1 →+1.155+0.755<.001<.00139
GBMTOP2A →+1.680+0.731<.001<.00139
GBMFANCI →+1.182+0.706<.001.00139
GBMPLK4 →+1.172+0.849<.001<.00139
UCECCDCA5 →+0.955+0.315<.001<.00139
LUADCHEK1 →+0.978+0.416<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,491 associations by consensus.

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