Across TCGA patient cohorts, PRICKLE2-AS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,651 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRICKLE2-AS3-associated proteins across cancer lineages are PRICKLE2_S806, AFAP1_S548, and FARP1. Each is linked with PRICKLE2-AS3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRICKLE2-AS3-to-partner and partner-to-PRICKLE2-AS3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRICKLE2-AS3→partner) and Y-score (partner→PRICKLE2-AS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRICKLE2_S806 →	+0.800	+1.036	<.001	<.001	3	7
LSCC	AFAP1_S548 →	+0.646	+0.675	<.001	<.001	3	6
HNSC	FARP1 →	+0.373	+0.727	<.001	<.001	3	6
BRCA	FERMT2 →	+0.482	+0.097	<.001	<.001	3	6
LSCC	FKBP7 →	+0.447	+0.559	<.001	<.001	3	6
UCEC	HDGFL3 →	+0.666	+0.817	.002	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,651 associations by consensus.

Exploration

PRICKLE2-AS3 survival (RNA) · tumor vs normal (RNA) · all PRICKLE2-AS3 data types