PRG4

Across TCGA patient cohorts, PRG4 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,083 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRG4-associated proteins across cancer lineages are OGN, TNS2_S120, and PRKG1. Each is linked with PRG4 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRG4-to-partner and partner-to-PRG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRG4 versus OGN in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRG4→partner) and Y-score (partner→PRG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	OGN →	+1.323	+0.426	<.001	.003	3	8
BRCA	TNS2_S120 →	+0.721	+1.309	<.001	<.001	3	7
OV	PRKG1 →	+0.606	+0.883	.001	.003	3	7
COAD	SORBS3 →	+0.338	+0.258	<.001	.001	3	7
OV	CPA3 →	+0.958	+0.784	<.001	<.001	3	7
PDAC	DPT →	+0.632	+0.497	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,083 associations by consensus.

PRG4 vs OGN — GBM

Explore this scatter interactively →