Across TCGA patient cohorts, PRELP protein abundance is significantly associated with the RNA expression of many other genes, with 13,095 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRELP-associated genes across cancer lineages are SMOC2, PTGIS, and INMT. Each is linked with PRELP in more than 9 cancer types. Because this analysis shows association rather than direction, both PRELP-to-partner and partner-to-PRELP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRELP→partner) and Y-score (partner→PRELP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SMOC2 →	+1.639	+1.108	<.001	<.001	3	10
UCEC	PTGIS →	+1.614	+0.905	<.001	<.001	3	10
BRCA	INMT →	+1.002	+0.928	<.001	<.001	3	10
CCRCC	LINC00924 →	+0.803	+0.988	<.001	<.001	3	10
PDAC	NALCN →	+0.771	+1.049	<.001	<.001	3	9
OV	SFRP4 →	+2.300	+0.980	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,095 associations by consensus.

Exploration

PRELP survival (RNA) · tumor vs normal (RNA) · all PRELP data types