Across TCGA patient cohorts, PRELP mutation is significantly associated with the RNA expression of many other genes, with 1,260 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRELP-associated genes across cancer lineages are SNORD116-3, RNA5SP73, and SPATA8-AS1. Each is linked with PRELP in more than 1 cancer types. Because this analysis shows association rather than direction, both PRELP-to-partner and partner-to-PRELP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRELP→partner) and Y-score (partner→PRELP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	SNORD116-3 →	+0.316	+4.564	.002	.004	3	2
CESC	RNA5SP73 →	+0.306	+5.252	<.001	.002	3	2
CESC	SPATA8-AS1 →	+0.070	+4.384	.006	.008	3	2
UCEC	PRAP1 →	-0.874	-1.938	.009	.001	3	2
UCEC	TOP3A →	+0.459	+2.960	<.001	<.001	3	2
BRCA	IGLVIV-59 →	+0.972	+5.926	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,260 associations by consensus.

Exploration

PRELP survival (RNA) · tumor vs normal (RNA) · all PRELP data types