PRELID1

Across TCGA patient cohorts, PRELID1 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible PRELID1-associated genes across cancer lineages are MIR7159, OR8B4, and OFD1P11Y. Each is linked with PRELID1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRELID1-to-partner and partner-to-PRELID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7159 grouped by PRELID1-low versus PRELID1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRELID1→partner) and Y-score (partner→PRELID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR7159 →	+0.624	+6.676	<.001	<.001	3	1
SKCM	OR8B4 →	+0.039	+7.816	<.001	.008	3	1
SKCM	OFD1P11Y →	+0.039	+7.816	<.001	.008	3	1
SKCM	HMGB3P16 →	+0.124	+7.816	<.001	.008	3	1
SKCM	MIR3152 →	+0.478	+7.816	<.001	.008	3	1
SKCM	MRPS5P4 →	+0.139	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

MIR7159 by PRELID1 expression — LIHC

Explore this box plot interactively →