PREB

Across TCGA pan-cancer cohorts, PREB Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PREB data layer compared with 29 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PREB Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated PREB expression acts as an unfavorable survival marker.

STAD and COAD are the cancer types where PREB Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	II,III,IV	0.284	0.694	.011	9	view →
COAD	DFS	Median	II,III,IV	0.230	0.648	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PREB–STAD (DFS)

Open the STAD breakdown →