PRDX6

Across TCGA patient cohorts, PRDX6 protein abundance is significantly associated with the RNA expression of many other genes, with 11,654 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRDX6-associated genes across cancer lineages are EPHX1, FTCDNL1, and BCL2A1. Each is linked with PRDX6 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRDX6-to-partner and partner-to-PRDX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDX6 versus EPHX1 in LUAD, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDX6→partner) and Y-score (partner→PRDX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	EPHX1 →	+1.050	+0.281	<.001	<.001	3	7
LSCC	FTCDNL1 →	+1.000	+0.353	<.001	<.001	3	6
OV	BCL2A1 →	-1.260	-0.474	<.001	<.001	3	5
LSCC	CXCL8 →	-1.855	-0.360	<.001	<.001	3	5
GBM	PRDX6-AS1 →	+0.623	+0.399	<.001	<.001	3	5
GBM	GHR →	+0.753	+0.347	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,654 associations by consensus.

PRDX6 vs EPHX1 — LUAD

Explore this scatter interactively →