Across TCGA patient cohorts, PRDX6-AS1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRDX6-AS1-associated genes across cancer lineages are F8A2, MIR4769, and MIR6076. Each is linked with PRDX6-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRDX6-AS1-to-partner and partner-to-PRDX6-AS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDX6-AS1→partner) and Y-score (partner→PRDX6-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	F8A2 →	+0.062	+4.694	<.001	.007	3	1
UCEC	MIR4769 →	+0.772	+5.027	<.001	.004	3	1
UCEC	MIR6076 →	+0.798	+4.552	<.001	.005	3	1
UCEC	RNU6-399P →	+0.489	+4.621	.003	.008	3	1
UCEC	NXT1P1 →	+0.360	+4.233	<.001	.009	3	1
UCEC	C1QBPP1 →	+0.111	+4.621	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

PRDX6-AS1 survival (RNA) · tumor vs normal (RNA) · all PRDX6-AS1 data types