PRDX3

Across TCGA patient cohorts, PRDX3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,118 significant associations in total. OV shows the largest number of these associations.

The most reproducible PRDX3-associated genes across cancer lineages are SFXN4, TREM1, and FPR2. Each is linked with PRDX3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRDX3-to-partner and partner-to-PRDX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDX3 versus SFXN4 in LUAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDX3→partner) and Y-score (partner→PRDX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SFXN4 →	+0.509	+0.278	<.001	<.001	3	6
COAD	TREM1 →	-1.273	-0.343	<.001	<.001	3	5
COAD	FPR2 →	-1.168	-0.334	.001	<.001	3	5
COAD	SRSF3 →	-0.517	-0.413	<.001	<.001	3	4
LUAD	ZNF430 →	-0.466	-0.307	<.001	.001	3	4
LUAD	ECHS1 →	+0.410	+0.307	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,118 associations by consensus.

PRDX3 vs SFXN4 — LUAD

Explore this scatter interactively →