PRDX2P3

Across TCGA pan-cancer cohorts, PRDX2P3 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PRDX2P3 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PRDX2P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PRDX2P3 expression acts as an unfavorable survival marker, although some lineages such as UCEC and UCS show a favorable association.

UVM, ACC, and UCEC are the cancer types where PRDX2P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	III,IV	0.327	0.700	.001	42	view →
ACC	OS	Median	All	0.661	0.947	.004	39	view →
UCEC	OS	Median	IV	0.670	0.207	<.001	36	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
SKCM	DFS	Tertile	III,IV	0.357	0.624	.013	14	view →
PCPG	OS	Quartile	All	0.879	1.000	.009	14	view →
BRCA	DFS	Quartile	III,IV	0.951	0.804	.007	12	view →
MESO	DFS	Tertile	All	0.276	0.457	.015	12	view →
THYM	DFS	Tertile	II,III,IV	0.961	0.645	.009	11	view →
STAD	DFS	Quartile	IV	0.180	0.631	.024	9	view →
KICH	DFS	Tertile	II,III,IV	0.220	0.832	.020	6	view →
COAD	OS	Quartile	IV	0.653	0.317	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PRDX2P3–UVM (DFS)

Open the UVM breakdown →