PRDM13

Across TCGA cell cohorts, PRDM13 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,987 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PRDM13-associated GO terms across cancer lineages are Ribosomal small subunit biogenesis, Ribosome biogenesis, and rRNA processing. Each is linked with PRDM13 in more than 8 cancer types. Because this analysis shows association rather than direction, both PRDM13-to-partner and partner-to-PRDM13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal small subunit biogenesis grouped by PRDM13-low versus PRDM13-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM13→partner) and Y-score (partner→PRDM13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Ribosomal small subunit biogenesis →	+0.062	+0.513	<.001	.003	3	9
SKIN	Ribosome biogenesis →	+0.066	+0.462	<.001	.006	3	9
OESOPHAGUS	rRNA processing →	+0.070	+0.559	.008	.009	3	9
SKIN	Ribosome assembly →	+0.058	+0.488	<.001	.005	3	9
BREAST	rRNA metabolic process →	+0.057	+0.346	<.001	.005	3	8
OESOPHAGUS	Protein-RNA complex assembly →	+0.074	+0.815	.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,987 associations by consensus.

Ribosomal small subunit biogenesis by PRDM13 expression — SKIN

Explore this box plot interactively →