PRDM12

Across TCGA patient cohorts, PRDM12 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,085 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRDM12-associated GO terms across cancer lineages are Outer mitochondrial membrane organization, Obsolete histone H3-K9 methylation, and Acrosomal vesicle exocytosis. Each is linked with PRDM12 in more than 18 cancer types. Because this analysis shows association rather than direction, both PRDM12-to-partner and partner-to-PRDM12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Outer mitochondrial membrane organization grouped by PRDM12-low versus PRDM12-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM12→partner) and Y-score (partner→PRDM12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Outer mitochondrial membrane organization →	+0.048	+0.114	<.001	<.001	3	19
GBM	Obsolete histone H3-K9 methylation →	-0.050	-0.272	<.001	<.001	2	19
LAML	Acrosomal vesicle exocytosis →	+0.079	+0.127	<.001	<.001	2	18
DLBC	sno(s)RNA processing →	+0.058	+0.141	.002	.003	3	16
KICH	L-proline biosynthetic process →	+0.081	+0.124	.002	.005	3	15
STAD	Poly(A)-dependent snoRNA 3'-end processing →	+0.059	+0.215	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,085 associations by consensus.

Outer mitochondrial membrane organization by PRDM12 expression — UVM

Explore this box plot interactively →