PRDM12

Across TCGA cell cohorts, PRDM12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,827 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRDM12-associated GO terms across cancer lineages are Cap-dependent translational initiation, Oxaloacetate metabolic process, and Immune response-regulating cell surface receptor signaling pathway. Each is linked with PRDM12 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRDM12-to-partner and partner-to-PRDM12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cap-dependent translational initiation grouped by PRDM12-low versus PRDM12-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM12→partner) and Y-score (partner→PRDM12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cap-dependent translational initiation →	+0.104	+2.582	<.001	<.001	3	7
OESOPHAGUS	Oxaloacetate metabolic process →	+0.153	+0.161	<.001	.007	2	8
SOFT_TISSUE	Immune response-regulating cell surface receptor signaling pathway →	-0.040	-1.353	<.001	.001	3	7
URINARY_TRACT	Negative regulation of voltage-gated calcium channel activity →	-0.204	-0.212	.001	<.001	3	7
URINARY_TRACT	Cell differentiation involved in embryonic placenta development →	-0.153	-0.206	.001	.004	3	7
BONE	Modification of postsynaptic actin cytoskeleton →	-0.119	-0.110	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,827 associations by consensus.

Cap-dependent translational initiation by PRDM12 expression — SOFT_TISSUE

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