PRDM11

Across TCGA patient cohorts, PRDM11 protein abundance is significantly associated with the RNA expression of many other genes, with 4,833 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRDM11-associated genes across cancer lineages are TSPY26P, BCAS4, and SYT14. Each is linked with PRDM11 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRDM11-to-partner and partner-to-PRDM11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDM11 versus TSPY26P in CCRCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM11→partner) and Y-score (partner→PRDM11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TSPY26P →	+0.973	+0.537	<.001	.001	3	3
HNSC	BCAS4 →	+0.770	+1.215	.003	<.001	3	2
HNSC	SYT14 →	+1.452	+0.939	.001	.002	3	2
HNSC	SCD5 →	+1.565	+0.890	.006	.006	3	2
HNSC	EGFR →	+1.140	+0.714	.009	.002	3	2
HNSC	BSG →	-1.020	-1.162	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,833 associations by consensus.

PRDM11 vs TSPY26P — CCRCC

Explore this scatter interactively →