PRDM11

Across TCGA cell cohorts, PRDM11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,166 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRDM11-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Negative regulation of calcium ion export across plasma membrane, and Nucleic acid transport. Each is linked with PRDM11 in more than 13 cancer types. Because this analysis shows association rather than direction, both PRDM11-to-partner and partner-to-PRDM11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by PRDM11-low versus PRDM11-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM11→partner) and Y-score (partner→PRDM11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	mRNA alternative polyadenylation →	+0.093	+1.143	<.001	<.001	3	14
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.096	+1.004	<.001	<.001	3	14
OESOPHAGUS	Nucleic acid transport →	+0.144	+1.376	<.001	<.001	3	14
OESOPHAGUS	RNA transport →	+0.144	+1.376	<.001	<.001	3	14
PANCREAS	RNA localization →	+0.093	+0.963	<.001	<.001	3	14
OESOPHAGUS	mRNA export from nucleus →	+0.127	+0.967	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,166 associations by consensus.

mRNA alternative polyadenylation by PRDM11 expression — SOFT_TISSUE

Explore this box plot interactively →