Across TCGA patient cohorts, PRCD mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRCD-associated genes across cancer lineages are RPS10-NUDT3, RNA5SP414, and IGHV4-4. Each is linked with PRCD in more than 1 cancer types. Because this analysis shows association rather than direction, both PRCD-to-partner and partner-to-PRCD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRCD→partner) and Y-score (partner→PRCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS10-NUDT3 →	+0.421	+3.531	<.001	.005	3	1
UCEC	RNA5SP414 →	+0.894	+2.933	<.001	.006	3	1
UCEC	IGHV4-4 →	+1.197	+2.953	.001	.007	3	1
UCEC	MIR7845 →	+0.574	+3.160	<.001	.002	3	1
UCEC	SNX3P1Y →	+0.199	+5.671	<.001	<.001	3	1
UCEC	RNU6-1082P →	+0.328	+3.551	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

PRCD survival (RNA) · tumor vs normal (RNA) · all PRCD data types