Across TCGA patient cohorts, PRCD mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRCD-associated genes across cancer lineages are Neutrophils, Th2 cells, and Epithelial cells. Each is linked with PRCD in more than 1 cancer types. Because this analysis shows association rather than direction, both PRCD-to-partner and partner-to-PRCD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRCD→partner) and Y-score (partner→PRCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Neutrophils →	+0.018	+2.488	.001	.012	3	2
UCEC	Th2 cells →	+0.346	+2.815	<.001	.036	3	1
UCEC	Epithelial cells →	-0.107	-3.000	.010	.037	2	1
UCEC	Basophils →	+0.203	+3.000	.039	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

PRCD survival (RNA) · tumor vs normal (RNA) · all PRCD data types