PRC1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,292 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRC1-associated proteins across cancer lineages are SMC4, CDK1, and FEN1. Each is linked with PRC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PRC1-to-partner and partner-to-PRC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRC1→partner) and Y-score (partner→PRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADSMC4 →+0.604+0.284<.001<.001310
LUADCDK1 →+0.851+0.296<.001<.001310
OVFEN1 →+0.550+0.405<.001<.001310
HNSCRFC2 →+0.520+0.517<.001<.00139
LUADRRM2 →+0.824+0.279<.001<.00139
UCECSMC2 →+0.659+0.459<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,292 associations by consensus.

Exploration