PRAP1

Across TCGA patient cohorts, PRAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,159 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible PRAP1-associated GO terms across cancer lineages are Polyamine metabolic process, Proton motive force-driven ATP synthesis, and Organic acid catabolic process. Each is linked with PRAP1 in more than 20 cancer types. Because this analysis shows association rather than direction, both PRAP1-to-partner and partner-to-PRAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Polyamine metabolic process grouped by PRAP1-low versus PRAP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAP1→partner) and Y-score (partner→PRAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Polyamine metabolic process →	+0.049	+2.614	<.001	<.001	3	21
UVM	Proton motive force-driven ATP synthesis →	+0.050	+0.425	<.001	<.001	3	18
CHOL	Organic acid catabolic process →	+0.059	+4.037	<.001	<.001	3	18
TGCT	Mitochondrial transport →	+0.029	+1.356	<.001	<.001	3	18
UVM	NADH dehydrogenase complex assembly →	+0.042	+0.316	<.001	<.001	2	18
UVM	ATP synthesis coupled electron transport →	+0.056	+0.486	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,159 associations by consensus.

Polyamine metabolic process by PRAP1 expression — ESCA

Explore this box plot interactively →