PRAP1

Across TCGA patient cohorts, PRAP1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PRAP1-associated genes across cancer lineages are naive B-cells, Osteoblast, and Preadipocytes. Each is linked with PRAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRAP1-to-partner and partner-to-PRAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, naive B-cells grouped by PRAP1-low versus PRAP1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAP1→partner) and Y-score (partner→PRAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	naive B-cells →	+0.016	+4.922	<.001	.010	3	1
LUAD	Osteoblast →	+0.030	+3.494	.036	.030	3	1
COAD	Preadipocytes →	+0.035	+2.754	.003	.024	3	1
UCEC	Pericytes →	+0.048	+2.113	.003	.044	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

naive B-cells by PRAP1 expression — CESC

Explore this box plot interactively →