PRAMEF6

Across TCGA patient cohorts, PRAMEF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,458 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF6-associated GO terms across cancer lineages are Mitochondrial gene expression, Mitochondrial respiratory chain complex assembly, and Regulation of generation of precursor metabolites and energy. Each is linked with PRAMEF6 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRAMEF6-to-partner and partner-to-PRAMEF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by PRAMEF6-low versus PRAMEF6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF6→partner) and Y-score (partner→PRAMEF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.119	+0.035	<.001	<.001	3	7
STAD	Mitochondrial respiratory chain complex assembly →	+0.121	+0.036	<.001	<.001	3	7
STAD	Regulation of generation of precursor metabolites and energy →	+0.099	+0.033	<.001	<.001	3	7
STAD	Ribose phosphate biosynthetic process →	+0.110	+0.031	<.001	<.001	3	7
STAD	tRNA 5'-end processing →	+0.098	+0.031	<.001	<.001	3	7
STAD	Pseudouridine synthesis →	+0.095	+0.032	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,458 associations by consensus.

Mitochondrial gene expression by PRAMEF6 expression — STAD

Explore this box plot interactively →