PRAMEF26

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PRAMEF26 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PRAMEF26-associated genes across cancer lineages are SCN10A. Each is linked with PRAMEF26 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRAMEF26-to-partner and partner-to-PRAMEF26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCN10A grouped by PRAMEF26-low versus PRAMEF26-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF26→partner) and Y-score (partner→PRAMEF26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCSCN10A →+0.063+5.029<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SCN10A by PRAMEF26 expression — LUNG_SCLC

Box plot of SCN10A in PRAMEF26-low vs PRAMEF26-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration