PRAMEF11

Across TCGA patient cohorts, PRAMEF11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,119 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF11-associated GO terms across cancer lineages are Negative regulation of protein binding, Mitochondrial respiratory chain complex assembly, and Protein targeting to membrane. Each is linked with PRAMEF11 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRAMEF11-to-partner and partner-to-PRAMEF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein binding grouped by PRAMEF11-low versus PRAMEF11-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF11→partner) and Y-score (partner→PRAMEF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of protein binding →	+0.109	+0.023	<.001	<.001	3	7
STAD	Mitochondrial respiratory chain complex assembly →	+0.136	+0.019	<.001	<.001	3	7
STAD	Protein targeting to membrane →	+0.110	+0.024	<.001	<.001	3	7
STAD	Nucleoside phosphate biosynthetic process →	+0.110	+0.029	<.001	<.001	3	7
STAD	Mitochondrial transport →	+0.119	+0.029	<.001	.002	3	7
STAD	Ribosomal small subunit biogenesis →	+0.136	+0.025	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,119 associations by consensus.

Negative regulation of protein binding by PRAMEF11 expression — STAD

Explore this box plot interactively →