PRAM1

Across TCGA patient cohorts, PRAM1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,450 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRAM1-associated genes across cancer lineages are CSF2RB, MEFV, and CSF3R. Each is linked with PRAM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PRAM1-to-partner and partner-to-PRAM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRAM1 versus CSF2RB in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAM1→partner) and Y-score (partner→PRAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CSF2RB →	+1.108	+0.785	.001	.008	3	10
LSCC	MEFV →	+0.940	+0.609	<.001	<.001	3	10
GBM	CSF3R →	+1.356	+0.677	<.001	<.001	3	10
OV	LILRB2 →	+1.233	+1.043	<.001	<.001	3	10
GBM	MYO1F →	+0.987	+0.640	<.001	<.001	3	10
GBM	LILRB3 →	+1.013	+0.494	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,450 associations by consensus.

PRAM1 vs CSF2RB — OV

Explore this scatter interactively →