PRAL

Across TCGA patient cohorts, PRAL RNA expression is significantly associated with the protein abundance of many other proteins, with 10,218 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PRAL-associated proteins across cancer lineages are ISG15, MX2, and NMI. Each is linked with PRAL in more than 9 cancer types. Because this analysis shows association rather than direction, both PRAL-to-partner and partner-to-PRAL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRAL versus ISG15 in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAL→partner) and Y-score (partner→PRAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ISG15 →	+0.998	+0.573	<.001	<.001	3	10
LSCC	MX2 →	+0.865	+0.552	<.001	<.001	3	10
BRCA	NMI →	+0.587	+0.373	<.001	<.001	3	10
LSCC	STAT1 →	+0.721	+0.530	<.001	<.001	3	10
LSCC	OAS2 →	+0.976	+0.557	<.001	<.001	3	10
BRCA	PARP14 →	+0.422	+0.356	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,218 associations by consensus.

PRAL vs ISG15 — GBM

Explore this scatter interactively →