PRAC1

Across TCGA cell cohorts, PRAC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,457 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRAC1-associated GO terms across cancer lineages are Intraciliary transport, Negative regulation of testosterone biosynthetic process, and Morphogenesis of an epithelium. Each is linked with PRAC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRAC1-to-partner and partner-to-PRAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary transport grouped by PRAC1-low versus PRAC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAC1→partner) and Y-score (partner→PRAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Intraciliary transport →	+0.065	+3.764	<.001	.003	3	4
BONE	Negative regulation of testosterone biosynthetic process →	-0.216	-5.209	<.001	<.001	3	4
BONE	Morphogenesis of an epithelium →	-0.054	-4.327	<.001	<.001	3	4
BONE	Retinal ganglion cell axon guidance →	-0.305	-4.827	<.001	.002	3	4
BONE	Regulation of CD4-positive, alpha-beta T cell proliferation →	-0.231	-5.297	<.001	<.001	3	3
BONE	Negative regulation of cell-substrate adhesion →	-0.130	-6.572	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,457 associations by consensus.

Intraciliary transport by PRAC1 expression — BONE

Explore this box plot interactively →