PPTC7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PPTC7 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,744 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPTC7-associated proteins across cancer lineages are CLIP1, LARP4_S722, and PPP2R5E_S33. Each is linked with PPTC7 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPTC7-to-partner and partner-to-PPTC7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPTC7→partner) and Y-score (partner→PPTC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACLIP1 →+0.234+0.416<.001.00135
LUADLARP4_S722 →+0.463+0.399.001<.00134
CCRCCPPP2R5E_S33 →-0.722-0.643<.001<.00134
LSCCDDX21 →+0.499+0.500<.001<.00134
UCECWDR36 →+0.212+0.505<.001<.00134
LSCCNAA25 →+0.275+0.452<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,744 associations by consensus.

Exploration