PPT2-EGFL8

Across TCGA patient cohorts, PPT2-EGFL8 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,142 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPT2-EGFL8-associated proteins across cancer lineages are ZNF318_S709, WRNIP1, and DHX16. Each is linked with PPT2-EGFL8 in more than 5 cancer types. Because this analysis shows association rather than direction, both PPT2-EGFL8-to-partner and partner-to-PPT2-EGFL8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPT2-EGFL8 versus ZNF318_S709 in LSCC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPT2-EGFL8→partner) and Y-score (partner→PPT2-EGFL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF318_S709 →	+0.537	+0.165	.002	.001	3	6
LSCC	WRNIP1 →	+0.304	+0.134	<.001	<.001	3	5
LSCC	DHX16 →	+0.225	+0.146	<.001	<.001	3	5
GBM	DHX9 →	+0.262	+0.180	<.001	<.001	3	5
LSCC	ZNF318 →	+0.348	+0.191	.002	<.001	3	4
GBM	NIPBL →	+0.235	+0.153	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,142 associations by consensus.

PPT2-EGFL8 vs ZNF318_S709 — LSCC

Explore this scatter interactively →