PPT2-EGFL8

Across TCGA pan-cancer cohorts, PPT2-EGFL8 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated PPT2-EGFL8 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PPT2-EGFL8 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PPT2-EGFL8 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

HNSC, ACC, and KIRC are the cancer types where PPT2-EGFL8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.483	0.280	<.001	102	view →
ACC	DFS	Median	All	0.251	0.621	<.001	72	view →
KIRC	DFS	Median	II,III,IV	0.409	0.609	.001	63	view →
COAD	DFS	Median	All	0.598	0.772	<.001	63	view →
PAAD	DFS	Tertile	II,III,IV	0.545	0.268	.001	46	view →
READ	OS	Median	All	0.776	0.519	.003	43	view →
LIHC	DFS	Quartile	All	0.397	0.606	<.001	39	view →
STAD	DFS	Median	III,IV	0.359	0.629	.002	35	view →
PRAD	DFS	Median	All	0.834	0.929	<.001	32	view →
THYM	DFS	Quartile	All	0.966	0.367	<.001	30	view →
UCS	DFS	Tertile	IV	0.932	0.361	.024	28	view →
BLCA	OS	Tertile	All	0.218	0.602	.006	24	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

PPT2-EGFL8–HNSC (OS)

Open the HNSC breakdown →