PPP4R4

Across TCGA patient cohorts, PPP4R4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,076 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP4R4-associated proteins across cancer lineages are PPP4R4_S775, YBX1, and NGDN. Each is linked with PPP4R4 in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP4R4-to-partner and partner-to-PPP4R4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP4R4 versus PPP4R4_S775 in LSCC, with a Pearson correlation of 0.93.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP4R4→partner) and Y-score (partner→PPP4R4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPP4R4_S775 →	+2.321	+2.177	<.001	<.001	3	8
GBM	YBX1 →	-0.328	-0.803	<.001	<.001	3	4
COAD	NGDN →	-0.576	-0.240	.001	.009	3	4
BRCA	RPS5 →	-0.293	-1.455	<.001	<.001	3	4
BRCA	RRP15 →	-0.359	-0.981	<.001	.002	3	4
LSCC	SLC9A1_S693 →	+0.454	+0.835	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,076 associations by consensus.

PPP4R4 vs PPP4R4_S775 — LSCC

Explore this scatter interactively →