PPP4R4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PPP4R4 protein abundance is significantly associated with the RNA expression of many other genes, with 5,062 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP4R4-associated genes across cancer lineages are LINC01547, LINC01700, and LINC02560. Each is linked with PPP4R4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP4R4-to-partner and partner-to-PPP4R4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP4R4 versus LINC01547 in PDAC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP4R4→partner) and Y-score (partner→PPP4R4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACLINC01547 →-0.656-0.949.007<.00132
PDACLINC01700 →+0.215+1.014.001.00232
LSCCLINC02560 →-0.701-0.786.008.00632
PDACDHX33 →-0.630-1.039.002.00132
LSCCGARS1 →-0.560-0.949<.001<.00132
LSCCBLMH →-0.843-0.815<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,062 associations by consensus.

PPP4R4 vs LINC01547 — PDAC

Per-sample scatter of PPP4R4 vs LINC01547 in PDAC (Pearson r = -0.60).

Explore this scatter interactively →

Exploration