PPP4R3A

Across TCGA cell cohorts, PPP4R3A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,232 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP4R3A-associated GO terms across cancer lineages are Heterochromatin organization, Vesicle tethering, and Heterochromatin formation. Each is linked with PPP4R3A in more than 15 cancer types. Because this analysis shows association rather than direction, both PPP4R3A-to-partner and partner-to-PPP4R3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin organization grouped by PPP4R3A-low versus PPP4R3A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP4R3A→partner) and Y-score (partner→PPP4R3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Heterochromatin organization →	+0.068	+0.719	<.001	<.001	3	16
KIDNEY	Vesicle tethering →	+0.068	+0.761	.004	<.001	3	15
OVARY	Heterochromatin formation →	+0.069	+0.735	<.001	<.001	3	15
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.056	+0.710	<.001	<.001	3	15
BREAST	DNA-templated DNA replication maintenance of fidelity →	+0.102	+0.857	<.001	<.001	3	14
OESOPHAGUS	Regulation of Schwann cell differentiation →	+0.226	+0.814	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,232 associations by consensus.

Heterochromatin organization by PPP4R3A expression — OVARY

Explore this box plot interactively →