PPP2R5E

Across TCGA patient cohorts, PPP2R5E protein abundance is significantly associated with the RNA expression of many other genes, with 12,897 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R5E-associated genes across cancer lineages are ACTR10, PPM1A, and ATG14. Each is linked with PPP2R5E in more than 8 cancer types. Because this analysis shows association rather than direction, both PPP2R5E-to-partner and partner-to-PPP2R5E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R5E versus ACTR10 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5E→partner) and Y-score (partner→PPP2R5E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ACTR10 →	+0.587	+0.210	<.001	<.001	3	9
BRCA	PPM1A →	+0.474	+0.219	<.001	<.001	3	8
HNSC	ATG14 →	+0.496	+0.181	<.001	.001	3	8
BRCA	SLC39A9 →	+0.560	+0.148	<.001	.009	3	8
HNSC	JKAMP →	+0.524	+0.228	<.001	<.001	3	8
GBM	PSEN1 →	+0.437	+0.306	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,897 associations by consensus.

PPP2R5E vs ACTR10 — HNSC

Explore this scatter interactively →