PPP2R5E

Across TCGA cell cohorts, PPP2R5E RNA expression is significantly associated with the go_rna of many other GO terms, with 4,196 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP2R5E-associated GO terms across cancer lineages are Vesicle tethering to Golgi, Positive regulation of mRNA catabolic process, and Monoubiquitinated protein deubiquitination. Each is linked with PPP2R5E in more than 14 cancer types. Because this analysis shows association rather than direction, both PPP2R5E-to-partner and partner-to-PPP2R5E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering to Golgi grouped by PPP2R5E-low versus PPP2R5E-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5E→partner) and Y-score (partner→PPP2R5E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Vesicle tethering to Golgi →	+0.122	+0.771	.002	.003	3	15
LUNG_SCLC	Positive regulation of mRNA catabolic process →	+0.057	+0.733	.001	.002	3	15
STOMACH	Monoubiquitinated protein deubiquitination →	+0.158	+0.781	<.001	.001	2	15
OESOPHAGUS	Protein localization to condensed chromosome →	+0.172	+0.693	<.001	<.001	3	14
BONE	Protein catabolic process at synapse →	+0.125	+0.823	<.001	<.001	3	12
BONE	Protein catabolic process at postsynapse →	+0.125	+0.823	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,196 associations by consensus.

Vesicle tethering to Golgi by PPP2R5E expression — OESOPHAGUS

Explore this box plot interactively →