PPP2R5C

Across TCGA patient cohorts, PPP2R5C RNA expression is significantly associated with the protein abundance of many other proteins, with 16,942 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PPP2R5C-associated proteins across cancer lineages are BAG5, CDC42BPB, and AKT1. Each is linked with PPP2R5C in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP2R5C-to-partner and partner-to-PPP2R5C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R5C versus BAG5 in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5C→partner) and Y-score (partner→PPP2R5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BAG5 →	+0.315	+0.637	<.001	<.001	3	8
CCRCC	CDC42BPB →	+0.324	+0.327	<.001	<.001	3	8
OV	AKT1 →	+0.313	+0.344	.002	.008	3	7
LSCC	PPP4R3A →	+0.310	+0.364	<.001	<.001	3	7
CCRCC	CEP170B →	+0.275	+0.260	<.001	<.001	3	6
COAD	HSP90AA1 →	+0.274	+0.402	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,942 associations by consensus.

PPP2R5C vs BAG5 — HNSC

Explore this scatter interactively →