PPP2R5C

Across TCGA cell cohorts, PPP2R5C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,793 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP2R5C-associated GO terms across cancer lineages are Monoubiquitinated protein deubiquitination, Regulation of mitotic nuclear division, and Regulation of DNA damage checkpoint. Each is linked with PPP2R5C in more than 13 cancer types. Because this analysis shows association rather than direction, both PPP2R5C-to-partner and partner-to-PPP2R5C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monoubiquitinated protein deubiquitination grouped by PPP2R5C-low versus PPP2R5C-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5C→partner) and Y-score (partner→PPP2R5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Monoubiquitinated protein deubiquitination →	+0.130	+0.635	<.001	<.001	3	14
KIDNEY	Regulation of mitotic nuclear division →	+0.106	+1.082	<.001	<.001	3	12
OVARY	Regulation of DNA damage checkpoint →	+0.102	+0.628	.001	.001	3	11
BREAST	Regulation of mitotic sister chromatid segregation →	+0.126	+0.678	.005	<.001	3	11
URINARY_TRACT	Immunoglobulin heavy chain V-D-J recombination →	+0.184	+0.819	.005	.001	3	11
BREAST	Regulation of mitotic sister chromatid separation →	+0.126	+0.596	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,793 associations by consensus.

Monoubiquitinated protein deubiquitination by PPP2R5C expression — URINARY_TRACT

Explore this box plot interactively →