PPP2R3C

Across TCGA patient cohorts, PPP2R3C protein abundance is significantly associated with the protein abundance of many other proteins, with 6,021 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R3C-associated proteins across cancer lineages are CCT8_S537, CEP350, and ZC3HAV1L_S257. Each is linked with PPP2R3C in more than 3 cancer types. Because this analysis shows association rather than direction, both PPP2R3C-to-partner and partner-to-PPP2R3C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R3C versus CCT8_S537 in GBM, with a Pearson correlation of 0.61.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R3C→partner) and Y-score (partner→PPP2R3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCT8_S537 →	+0.944	+0.429	<.001	<.001	3	4
BRCA	CEP350 →	+0.210	+0.240	<.001	<.001	3	3
GBM	ZC3HAV1L_S257 →	+0.696	+0.400	<.001	<.001	3	2
UCEC	UBAP2L_T843 →	+0.923	+0.342	<.001	<.001	3	2
BRCA	UQCRC1 →	-0.590	-0.376	<.001	<.001	3	2
BRCA	UQCRC2 →	-0.495	-0.288	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,021 associations by consensus.

PPP2R3C vs CCT8_S537 — GBM

Explore this scatter interactively →