PPP2R2C

Across TCGA patient cohorts, PPP2R2C protein abundance is significantly associated with the RNA expression of many other genes, with 5,634 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R2C-associated genes across cancer lineages are APTX, CREB3, and RGP1. Each is linked with PPP2R2C in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP2R2C-to-partner and partner-to-PPP2R2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R2C versus APTX in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2C→partner) and Y-score (partner→PPP2R2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	APTX →	+0.624	+0.422	<.001	<.001	3	3
OV	CREB3 →	+0.592	+0.429	<.001	<.001	3	2
OV	RGP1 →	+0.512	+0.328	.007	.004	3	2
LSCC	BAG1 →	+0.768	+0.487	<.001	<.001	3	2
OV	ABHD17B →	+0.438	+0.341	<.001	<.001	3	2
LSCC	EXOSC3 →	+0.512	+0.346	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,634 associations by consensus.

PPP2R2C vs APTX — LSCC

Explore this scatter interactively →