PPP2R2C

Across TCGA cell cohorts, PPP2R2C RNA expression is significantly associated with the go_rna of many other GO terms, with 2,940 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PPP2R2C-associated GO terms across cancer lineages are Endosomal vesicle fusion, Regulation of isoprenoid metabolic process, and Sesquiterpenoid metabolic process. Each is linked with PPP2R2C in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP2R2C-to-partner and partner-to-PPP2R2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal vesicle fusion grouped by PPP2R2C-low versus PPP2R2C-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2C→partner) and Y-score (partner→PPP2R2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Endosomal vesicle fusion →	+0.070	+1.673	<.001	.001	3	8
KIDNEY	Regulation of isoprenoid metabolic process →	+0.203	+2.418	.001	.002	3	7
LUNG_NSCLC_LUAD	Sesquiterpenoid metabolic process →	+0.384	+1.970	<.001	<.001	3	7
OESOPHAGUS	Protein folding →	+0.074	+2.633	.005	.001	2	8
OESOPHAGUS	Respiratory electron transport chain →	+0.091	+2.362	.002	<.001	3	7
LUNG_NSCLC_LUSC	Postsynaptic intermediate filament cytoskeleton organization →	+1.531	+2.290	.003	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,940 associations by consensus.

Endosomal vesicle fusion by PPP2R2C expression — PANCREAS

Explore this box plot interactively →