PPP2R2B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PPP2R2B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,582 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R2B-associated proteins across cancer lineages are RTN1, GNB4, and KCTD12. Each is linked with PPP2R2B in more than 5 cancer types. Because this analysis shows association rather than direction, both PPP2R2B-to-partner and partner-to-PPP2R2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R2B versus RTN1 in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2B→partner) and Y-score (partner→PPP2R2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRTN1 →+0.522+0.299<.001<.00136
COADGNB4 →+0.341+0.236<.001<.00136
UCECKCTD12 →+0.578+0.425<.001.00136
GBMTMOD2 →+0.400+0.506<.001<.00136
BRCACOTL1 →+0.629+0.314<.001<.00135
COADDPYSL2 →+0.349+0.320<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,582 associations by consensus.

PPP2R2B vs RTN1 — COAD

Per-sample scatter of PPP2R2B vs RTN1 in COAD (Pearson r = 0.39).

Explore this scatter interactively →

Exploration