PPP2R2B

Across TCGA cell cohorts, PPP2R2B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,552 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPP2R2B-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Respiratory electron transport chain, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with PPP2R2B in more than 8 cancer types. Because this analysis shows association rather than direction, both PPP2R2B-to-partner and partner-to-PPP2R2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by PPP2R2B-low versus PPP2R2B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2B→partner) and Y-score (partner→PPP2R2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.149	+2.306	<.001	.003	3	9
LUNG_SCLC	Respiratory electron transport chain →	+0.087	+2.175	<.001	<.001	3	9
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.146	+2.129	<.001	.008	3	9
LUNG_SCLC	ATP synthesis coupled electron transport →	+0.093	+1.765	.001	.008	3	9
LUNG_SCLC	Mitochondrial ATP synthesis coupled electron transport →	+0.093	+1.765	.001	.008	3	9
STOMACH	Protein stabilization →	+0.090	+2.408	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,552 associations by consensus.

Negative regulation of myoblast fusion by PPP2R2B expression — STOMACH

Explore this box plot interactively →