PPP2CB

Across TCGA patient cohorts, PPP2CB protein abundance is significantly associated with the RNA expression of many other genes, with 9,045 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPP2CB-associated genes across cancer lineages are DCTN6, UBXN8, and SARAF. Each is linked with PPP2CB in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP2CB-to-partner and partner-to-PPP2CB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2CB versus DCTN6 in OV, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2CB→partner) and Y-score (partner→PPP2CB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DCTN6 →	+0.744	+0.480	<.001	.008	3	8
OV	UBXN8 →	+0.976	+0.712	<.001	<.001	3	8
BRCA	SARAF →	+0.799	+0.524	<.001	<.001	3	8
OV	ELP3 →	+0.955	+0.564	<.001	.001	3	8
OV	PPP2R2A →	+0.663	+0.508	<.001	.001	3	8
OV	LEPROTL1 →	+0.575	+0.513	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,045 associations by consensus.

PPP2CB vs DCTN6 — OV

Explore this scatter interactively →