PPP2CA

Across TCGA patient cohorts, PPP2CA RNA expression is significantly associated with the protein abundance of many other proteins, with 12,385 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPP2CA-associated proteins across cancer lineages are HSPA4, YTHDC2, and PHAX. Each is linked with PPP2CA in more than 6 cancer types. Because this analysis shows association rather than direction, both PPP2CA-to-partner and partner-to-PPP2CA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2CA versus HSPA4 in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2CA→partner) and Y-score (partner→PPP2CA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HSPA4 →	+0.325	+0.489	<.001	<.001	3	7
OV	YTHDC2 →	+0.316	+0.472	<.001	<.001	3	6
LSCC	PHAX →	+0.314	+0.337	<.001	<.001	3	5
OV	C5orf24 →	+0.302	+0.361	.002	.003	3	5
OV	RNF14 →	+0.336	+0.358	.001	.004	3	4
OV	KDM3B →	+0.347	+0.614	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,385 associations by consensus.

PPP2CA vs HSPA4 — OV

Explore this scatter interactively →